Endocrine Abstracts

Pregnancy in acromegalic patients is an infrequent event, but with earlier diagnosis and advanced surgical/medical management, more affected women get pregnant.The use of Somatostatin analogues (SSA) during pregnancy seems safe, but there are few reported pregnancies under this treatment.We report two acromegalic patients treated with SSA that became pregnant.Case 1: Thirty-three year old woman diagnosed with...

Introduction: Adrenal incidentaloma are becoming very frequent. Bilateral adrenocortical adenomas are a rare cause of ACTH-independent Cushing syndrome.Clinical case: A 64-year-old hypertensive woman presented with bilateral adrenal incidentaloma detected on the evaluation as a living kidney donor candidate. She was normotensive (129/87 mmHg) on monotherapy, BMI – 24.8 kg/m2, with no recent weight gain, hirsutism, striae or mood disturban...

Introduction: Pheochromocytoma is an uncommon tumor. Non-classical forms can make diagnosis difficult and delay correct management strategies.Case report: A 20-years old caucasian male presented to the emergency room with unproductive cough, fever and tiredness for 7 days. He was eupneic, afebrile, BP 176/115 mmHg, 104 bpm with inspiratory crepitations in the left lung base. Leucocyte–14.1×109/l (N 70%); platelets – 659×10<...

Introduction: Several recent studies have reported an increase in the incidence of thyroid cancer during the last decades. The delineation between low-risk and high-risk tumor size is not well defined. The purpose of this study was to evaluate the relationship between the primary tumor size of differentiated thyroid cancer and clinicopathologic data.Methods: We have analysed all records of all patients submitted to thyroidectomy at our hospital between 2...

Introduction: Recent data reveal that in the last 25 years it has been a 2.4 fold increase in thyroid cancer, with concomitant rise in thyroid microcarcinoma cases. The main purpose of this study was to analyse the surgical indications that leads to incidentally noted papillary microcarcinoma diagnosis.Methods: We analysed clinicopathologic data of nineteen cases of incidentally found papillary thyroid microcarcinoma, from 1244 thyroid surgeries realized...

Introduction: Parathyroid carcinoma is a rare cause of primary hyperparathyroidism. Initial complete surgical resection is crucial. Recurrence is common and primary cause of mortality is severe hypercalcemia.Clinical case: In 2006, a 51 years old male presented with multiple bone pain, anorexia and weight loss, calcium 11.7 mg/dl, PTH 189 pg/ml. Eight years before a diagnosis of atypical parathyroid adenoma was made after left inferior parathyroidectomy ...